August 2021 Top Biopharma Deal: RemeGen – Seagen HER2-targeted ADC, Disitamab Vedotin for Solid Tumors
Top Biopharma Partnership by Upfront Cash and Equity
RemeGen development and commercialization deal with Seagen for disitamab vedotin
Announced: August 9, 2021
Total Deal Value: $2,600M
Upfront Cash: $200M
Upfront Equity: n/a
Option Payments: n/a
Milestones: $2,400M (Dev., Reg., and Sales)
Royalty: Tiered, high single-digit to mid-teens
Cost and Profit Split: n/a
Phase II HER2-targeted ADC disitamab vedotin for the treatment of several solid tumor types including urothelial, gastric, and breast cancer.
Development and Commercial License
Development responsibility and costs split by territory.
- RemeGen granted Seagen exclusive, worldwide rights, excluding parts of Asia, to co-develop and commercialize HER2-targeted ADC, disitamab vedotin for the treatment of several solid tumor types including urothelial, gastric, and breast cancer.
- RemeGen will retain development and commercialization rights in Asia excluding Japan and Singapore and will be responsible for all submissions specific to its territory.
- Seagen will lead global clinical development and RemeGen will fund and operate clinical trials attributable to its territory.
- RemeGen will receive $200M up front and is eligible for up to $2.4B in development, regulatory, and commercialization milestones, plus undisclosed tiered, high single-digit to mid-teens royalties.
The Deal of the Month for July 2021 was Arvinas and Pfizer’s PROTAC deal with $1B up front for ARV-471. Read about it here.
DealForma’s Deal of the Month selection is based on the largest disclosed upfront cash and equity total in partnership deals involving R&D as announced in the month prior to this article. Data for this analysis was compiled using the DealForma biopharma deals database. All data are based on publicly disclosed figures and deal terms. We invite you to answer interesting questions on biopharma business development and licensing using our data and carefully curated profiles on deals, pipelines, companies, funding, and business executives by visiting dealforma.com to schedule your personalized demo.
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Biotech and pharma M&A total deal values slumped in 2020, despite an active year in life sciences dealmaking, with no big standout biopharma deals until late in the second half of the year. We look at the extensive DealForma database to see how life sciences M&A activity shaped up in 2020 in more detail.
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