August 2021 Top Biopharma Deal: RemeGen – Seagen HER2-targeted ADC, Disitamab Vedotin for Solid Tumors

by | Sep 8, 2021

Top Biopharma Partnership by Upfront Cash and Equity

August 2021

RemeGen development and commercialization deal with Seagen for disitamab vedotin

Announced: August 9, 2021

Total Deal Value: $2,600M

Upfront Cash: $200M

Upfront Equity: n/a

Option Payments: n/a

Milestones: $2,400M (Dev., Reg., and Sales)

Royalty: Tiered, high single-digit to mid-teens

Cost and Profit Split: n/a

The Asset:

Phase II HER2-targeted ADC disitamab vedotin for the treatment of several solid tumor types including urothelial, gastric, and breast cancer.

Deal Structure:

Development and Commercial License

Partnership Features:

Development responsibility and costs split by territory.

The Details:

  • RemeGen granted Seagen exclusive, worldwide rights, excluding parts of Asia, to co-develop and commercialize HER2-targeted ADC, disitamab vedotin for the treatment of several solid tumor types including urothelial, gastric, and breast cancer.
  • RemeGen will retain development and commercialization rights in Asia excluding Japan and Singapore and will be responsible for all submissions specific to its territory.
  • Seagen will lead global clinical development and RemeGen will fund and operate clinical trials attributable to its territory.
  • RemeGen will receive $200M up front and is eligible for up to $2.4B in development, regulatory, and commercialization milestones, plus undisclosed tiered, high single-digit to mid-teens royalties.

Last Month:

The Deal of the Month for July 2021 was Arvinas and Pfizer’s PROTAC deal with $1B up front for ARV-471. Read about it here.

DealForma’s Deal of the Month selection is based on the largest disclosed upfront cash and equity total in partnership deals involving R&D as announced in the month prior to this article. Data for this analysis was compiled using the DealForma biopharma deals database. All data are based on publicly disclosed figures and deal terms. We invite you to answer interesting questions on biopharma business development and licensing using our data and carefully curated profiles on deals, pipelines, companies, funding, and business executives by visiting dealforma.com to schedule your personalized demo.

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