Top Biopharma Deal March 2021: Debiopharm – Merck KGaA for Xevinapant for head and neck cancer
Top Biopharma Partnership by Upfront Cash and Equity
Debiopharm development and commercialization deal with Merck KGaA for Xevinapant
Announced: Mar. 1, 2021
Total Deal Value: $1,083M
Upfront Cash: $227M (EUR 188M)
Upfront Equity: n/d
Option Payments: n/a
Milestones: $856M (EUR 710M), reg. & sales
Phase III Xevinapant (Debio 1143) oral Inhibitor of Apoptosis Proteins (IAP) antagonist for the treatment of advanced squamous cell carcinoma of the head and neck.
Development and Commercial License
Shared costs for Phase III
- Debiopharm granted Merck exclusive, worldwide rights to develop and commercialize Xevinapant for the treatment of advanced squamous cell carcinoma of the head and neck.
- Both companies will co-fund the ongoing Phase III registrational TrilynX study.
- Debiopharm will receive EUR 188M ($227M) up front and is eligible to receive up to EUR 710M ($856M) in regulatory and commercial milestones, plus royalties.
The Deal of the Month for February 2021 was the Vir – GSK expansion in to influenza. Read about it here.
DealForma’s Deal of the Month selection is based on the largest disclosed upfront cash and equity total in partnership deals involving R&D as announced in the month prior to this article. Data for this analysis was compiled using the DealForma biopharma deals database. All data are based on publicly disclosed figures and deal terms. We invite you to answer interesting questions on biopharma business development and licensing using our data and carefully curated profiles on deals, pipelines, companies, funding, and business executives by visiting dealforma.com to schedule your personalized demo.
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Biotech and pharma M&A total deal values slumped in 2020, despite an active year in life sciences dealmaking, with no big standout biopharma deals until late in the second half of the year. We look at the extensive DealForma database to see how life sciences M&A activity shaped up in 2020 in more detail.
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